Interferon-gamma release assay

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  • Test for diagnosis latent tuberculosis infection
  • Unclear utility in children under 5 years
  • Levels often decline after treatment for LTBI or active tuberculosis, but remain positive

References

  1. ^  Jorge R. Ledesma, Jianing Ma, Peng Zheng, Jennifer M. Ross, Theo Vos, Hmwe H. Kyu. Interferon-gamma release assay levels and risk of progression to active tuberculosis: a systematic review and dose-response meta-regression analysis. BMC Infectious Diseases. 2021;21(1). doi:10.1186/s12879-021-06141-4.