Kaposi sarcoma-associated herpesvirus
From IDWiki
Background
- Seroprevalence variés by geography and group
- US general population 1-5%
- US men who have sex with men 15-20%
- US MSM with HIV 30-35%
- Some Mediterranean countries 10-20%
- Sub-Saharan African countries 30-80%
Clinical Manifestations
- Mostly asymptomatic
- Kaposi sarcoma
- Primary effusion lymphoma (PEL)
- Causes effusions isolated within the pleural, pericardial, or abdominal cavities
- Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI
- Multicentric Castleman disease (MCD)
- Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly
Management
- See Kaposi sarcoma
