Rothia

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Rothia /
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Background

  • Genus of Gram-positive coccobacilli that can form filamentous branches
  • Normal oral flora in humans
  • Associated with dental caries and periodontal disease
  • Species of importance include:
  • Risk factors for infection include immunocompromise, particularly hematologic malignancy and severe neutropenia
    • Other risk factors include diabetes mellitus, alcohol use disorder, chronic liver disease, and HIV infection

Clinical Manfestations

  • Rare causes of bacteremia and line infection, most in immunocompromised patients
  • Case reports of endocarditis, meningitis, peritonitis, bone and joint infections, pneumonia, skin and soft tissue infection, endophthalmitis, and prosthetic joint infection

References

  1. ^ diekema2014ro