Background
Genus of Gram-positive coccobacilli that can form filamentous branches
Normal oral flora in humans
Associated with dental caries and periodontal disease
Species of importance include:
Risk factors for infection include immunocompromise, particularly hematologic malignancy and severe neutropenia
Other risk factors include diabetes mellitus, alcohol use disorder, chronic liver disease, and HIV infection
Clinical Manfestations
Rare causes of bacteremia and line infection, most in immunocompromised patients
Case reports of endocarditis, meningitis, peritonitis, bone and joint infections, pneumonia, skin and soft tissue infection, endophthalmitis, and prosthetic joint infection