Herpes simplex pneumonitis

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Background

  • Pulmonary infection of HSV
  • Pathology shows intranuclear inclusion bodies or positive immunohistochemical stain

Investigations

  • CT chest shows one of three patterns: diffuse or multifocal ground-glass opacities, multifocal peribronchial consolidation, or a mixture of both1

Management

  • In mechanically ventilated patients with positive HSV PCR, acyclovir 5 to 10 mg/kg IV q8h for 14 days23

References

  1. ^  S Chong, T S Kim, E Y Cho. Herpes simplex virus pneumonia: high-resolution CT findings. The British Journal of Radiology. 2010;83(991):585-589. doi:10.1259/bjr/51409455.