| Organism
|
Disease
|
First-line treatment
|
Treatment if allergic
|
Treatment if pregnant
|
| Chlamydia trachomatis
|
chlamydia
|
azithromycin 1 g po once
|
|
azithromycin 1 g po once, or amoxicillin 500 mg po tid for 7 days
|
| Chlamydia trachomatis serovars L1, L2, L3
|
Lymphogranuloma venereum
|
doxycycline 100 mg PO for 3 weeks
|
|
erythromycin 500 mg PO qid for 3 weeks
|
| Haemophilus ducreyi
|
chancroid
|
azithromycin 1 g po once
|
ceftriaxone 250 mg IM once
|
usual treatment
|
| Klebsiella granulomatis
|
granuloma inguinale (donovanosis)
|
doxycycline 100 mg po bid for 3 weeks
|
|
erythromycin
|
| Mycoplasma genitalium
|
non-gonococcal urethritis/cervicitis
|
azithromycin 500 mg PO on day one, followed by 250 mg PO on days two to five
|
moxifloxacin 400 mg PO daily for 7 days
|
|
| Neisseria gonorrhoeae
|
gonorrhea
|
ceftriaxone 250 mg IM once + azithromycin 1 g PO once
|
gentamicin 240 mg IM once + azithromycin 2 g PO once
|
usual treatment
|
| Treponema pallidum pallidum
|
primary, secondary, and EL syphilis
|
penicillin 2.4 MU IM once
|
doxycycline 100 mg PO bid for 14 days
|
usual treatment
|
| LL and tertiary syphilis
|
penicillin 2.4 MU IM weekly for 3 weeks
|
desensitization or doxycycline 100 mg PO bid for 28 days
|
usual treatment
|
| neurosyphilis
|
penicillin 4 MU IV q4h for 10-14 days
|
desensitization
|
usual treatment
|
