Microbiology
- Negative-sense single-stranded RNA virus in the Filoviridae family
- The ebolavirus genus includes five species:
- Zaire ebolavirus (EBOV), the most common
- Bundibugyo ebolavirus (BDBV)
- Reston ebolavirus (RESTV)
- Sudan ebolavirus (SUDV)
- Taï Forest (or Cote d'Ivoire) ebolavirus (TAFV)
Clinical Manifestations
- Incubation period 2 to 21 days (generally 3 to 13 days)
- Fever, fatigue, myalgias, weakness, and dizziness
- EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
- Relapse can occur as uveitis or meningitis
Prognosis and Complications
- 33 to 75% mortality, depending mostly on supportive care
