Norovirus

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Background

Virology

  • Member of the Caliciviridae family of positive-sense single-stranded RNA viruses

Clinical Manifestations

  • Incubation period of 24-48 hours
  • Nausea and vomiting followed by profuse diarrhea
  • Illness lasts 12 to 72 hours
  • May have low-grade fevers

Management

  • Supportive care and appropriate isolation and outbreak management

Outbreak Management

Kaplan criteria

  • Identify outbreaks of gastroenteritis caused by norovirus without specific viral testing1
  • The criteria are:
    • Vomiting in more than half of affected patients
    • Mean or median incubation period between 24 and 48 hours
    • Mean or median duration of illness between 12 and 60 hours
    • No bacterial pathogen identified in stool

References

  1. ^  R. M. Turcios, M.-A. Widdowson, A. C. Sulka, P. S. Mead, R. I. Glass. Reevaluation of Epidemiological Criteria for Identifying Outbreaks of Acute Gastroenteritis Due to Norovirus: United States, 1998-2000. Clinical Infectious Diseases. 2006;42(7):964-969. doi:10.1086/500940.