Single-tablet regimens for HIV
From IDWiki
See also HIV treatment
| Brand name | NRTIs | Non-NRTI | Notes |
|---|---|---|---|
| Triumeq | abacavir / lamivudine | dolutegravir (INI) | Highest barrier to resistance. Need to test for HLA-B5701 allele before starting. Avoid in hepatitis B coinfection. |
| Atripla | tenofovir disoproxil fumarate / emtricitabine | efavirenz | Older regimen. Neuropsychiatric symptoms, possibly including suicide. |
| Complera | tenofovir disoproxil fumarate / emtricitabine | rilpivirine | Avoid with viral loads (>100,000) or low CD4 (<200). Pill must be taken with food (>400kcal) and without PPIs. |
| Stribild | tenofovir disoproxil fumarate / emtricitabine | elvitegravir/cobicistat (INI) | Includes a P450 inhibitor to boost elvitegravir levels, with resultant drug-drug interactions. Avoid if CrCl <70. |
| Genvoya | tenofovir alafenamide / emtricitabine | elvitegravir/cobicistat (INI) | See Stribild, above. |
| Biktarvy | tenofovir alafenamide / emtricitabine | bictegravir (INI) |
