Dosing of antimicrobials in obesity

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Calculating Body Weight

Statistic Equation (Male) Equation (Female) Notes
Body mass index (BMI) (kg/m2) weight, kg / (height, m)2
Body surface area (BSA) (m2) (height, cm × weight, kg / 3600)1/2
Ideal body weight (IBW) (kg) 50 + 2.3 × (inches over 5 ft) 45.5 + 2.3 × (inches over 5 ft)
Adjusted body weight (ABW) (kg) IBW + C × (TBW - IBW) C = 0.3 to 0.4
Lean body weight (LBW) (kg) 9270 × TBW / 6680 + 216 x BMI 9270 × TBW / 8780 + 244 x BMI
Fat-free weight (FFW) (kg) 0.00139 × (height, cm)2 - 0.0801 × R + 0.187 × TBW + 39.83 0.00151 × (height, cm)2 - 0.0344 × R + 0.14 × TBW - (0.158 × age) + 20.387 R = resistance

Further Reading

  • Comprehensive Guidance for Antibiotic Dosing in Obese Adults. Pharmacotherapy. 2017;37(11):1415-1431. doi: 10.1002/phar.2023
  • Dosing of antibiotics in obesity. Curr Opin Infect Dis. 2012;25(6):634-49. doi: 10.1097/QCO.0b013e328359a4c1