Tinidazole

Background

• Antiparasitic and antibiotic
• Active against protozoa and obligate anaerobic bacteria
• Known as Fasigyn (Pfizer), with 500 mg and 1000 mg tablets

Dosing

• Giardiasis: 2 g p.o. once
• Only available in Canada through the Special Access Program

Safety

• Similar to metronidazole, it can cause a disulfiram-like reaction when taken with alcohol
• Can cause anorexia, headache, vertigo, nausea/vomiting/diarrhea, abdominal pain, pruritus