Ciprofloxacin
From IDWiki
Background
- Fluoroquinolone antibiotic with antipseudomonal activity
- Inhibits CYP1A2
Clinical Breakpoints
- For the Enterobacteriaceae changed recently
- MIC of 1 previously reported as susceptible but had reports of reduced susceptibility in practice
- New cutoff is 0.5 for susceptibility
Safety
- Similar to other fluoroquinolones
- QTc prolongation may not be as much of a clinical concern at usual doses1
References
- ^ Weber Liu, Hugh G Dickson, Hany Dimitri, Yashodha Shankar Pani, Jayanathi Ramanathan, Dana West, Sarah Tima, Winston Thai. The effect of oral ciprofloxacin at conventional doses on the QT interval in a tertiary outpatient setting. Journal of Antimicrobial Chemotherapy. 2026;81(3). doi:10.1093/jac/dkag020.
