Cotton fever: Difference between revisions

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== Background ==
== Background ==
* Mimics sepsis in patients who inject drugs and filter those drugs through cotton balls, particularly associated with heroin
* Mimics sepsis in patients who inject drugs and filter those drugs through cotton balls, particularly associated with heroin
* [[Pantoea agglomerans]] on the cotton plant releases endotoxins before the plant is processed, which are then injected along with the recreational substance, resulting in a sepsis syndrome without infection


== Clinical Manifestations ==
== Clinical Manifestations ==

Latest revision as of 13:47, 11 October 2022

Background

  • Mimics sepsis in patients who inject drugs and filter those drugs through cotton balls, particularly associated with heroin
  • Pantoea agglomerans on the cotton plant releases endotoxins before the plant is processed, which are then injected along with the recreational substance, resulting in a sepsis syndrome without infection

Clinical Manifestations

  • Self-resolving fevers, leukocytosis, myalgias, and nausea/vomiting, with negative blood cultures
  • Usually within 10 to 30 minutes after injection, and self-limited

Further Reading