Metronidazole: Difference between revisions
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* Usually resolves in 2 weeks (but may take up to 24 weeks) |
* Usually resolves in 2 weeks (but may take up to 24 weeks) |
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* Usually reversible (about 75%) but takes time |
* Usually reversible (about 75%) but takes time |
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| + | === Neurotoxicity === |
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| + | * Can cause seizures and encephalopathy |
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| + | * MRI may show bilateral symmetric T2 hyperintense lesions, which resolve after cessation of metronidazole |
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[[Category:Antibiotics]] |
[[Category:Antibiotics]] |
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Latest revision as of 12:21, 20 September 2022
Adverse Drug Reactions
- Disulfiram-like reaction with alcohol ingestion
Peripheral Neuropathy
- Starts after 4 weeks or 42 grams
- Free radicals causing nerve damage, and metronidazole causes degeneration
- Usually resolves in 2 weeks (but may take up to 24 weeks)
- Usually reversible (about 75%) but takes time
Neurotoxicity
- Can cause seizures and encephalopathy
- MRI may show bilateral symmetric T2 hyperintense lesions, which resolve after cessation of metronidazole
