Spinal hardware infection: Difference between revisions

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== Background ==

* Also known as postoperative spinal implant infection

== Classification ==
{| class="wikitable"
!Classification
!Acute Infection
!Chronic Infection
|-
|Pathogenesis: post-interventional
|<6 weeks post-interventionally (early onset)
|≥6 weeks post-interventionally (late onset)
|-
|Pathogenesis: hematogenous or per continuitatem
|<6 weeks of symptoms
|≥6 weeks of symptoms
|-
|Clinical presentation
|acute pain, fever, prolonged wound secretion (>7-10 days), acute neurological deficits
|chronic pain, implant migration or loosening, fistula, neurological deficits
|-
|Typical pathogens
|[[Staphylococcus aureus]], [[Streptococcus|Streptococcus species]], [[Gram-negative bacteria]]
|[[coagulase-negative staphylococci]], [[Cutibacterium acnes]]
|}

== Management ==

* For removal of all hardware, treat with 6 weeks total (at least 2 weeks IV)
* For retainment with plan for eradication, treat with 12 weeks total (at least 2 weeks IV)
* For single-stage replacement, treat with 12 weeks total (at least 2 weeks IV)
* For retainment with plan for eventual removal, treat with at least 2 weeks IV followed by oral suppression until hardware removal
* Chronic suppressive antibiotics should be considered with difficult-to-treat organisms

== Further Reading ==
== Further Reading ==


* [https://dx.doi.org/10.4103%2F2152-7806.120783 Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management]. ''Surg Neurol Int''. 2013;4(Suppl 5):S392-403.
* [https://dx.doi.org/10.4103%2F2152-7806.120783 Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management]. ''Surg Neurol Int''. 2013;4(Suppl 5):S392-403.
*Antibiotic treatment of postoperative spinal implant infections. ''J Spine Surg''. 2020;6(4):785–792. doi: [https://doi.org/10.21037/jss-20-456 10.21037/jss-20-456]


[[Category:Trauma and surgical patients]]
[[Category:Trauma and surgical patients]]

Revision as of 15:08, 10 March 2022

Background

  • Also known as postoperative spinal implant infection

Classification

Classification Acute Infection Chronic Infection
Pathogenesis: post-interventional <6 weeks post-interventionally (early onset) ≥6 weeks post-interventionally (late onset)
Pathogenesis: hematogenous or per continuitatem <6 weeks of symptoms ≥6 weeks of symptoms
Clinical presentation acute pain, fever, prolonged wound secretion (>7-10 days), acute neurological deficits chronic pain, implant migration or loosening, fistula, neurological deficits
Typical pathogens Staphylococcus aureus, Streptococcus species, Gram-negative bacteria coagulase-negative staphylococci, Cutibacterium acnes

Management

  • For removal of all hardware, treat with 6 weeks total (at least 2 weeks IV)
  • For retainment with plan for eradication, treat with 12 weeks total (at least 2 weeks IV)
  • For single-stage replacement, treat with 12 weeks total (at least 2 weeks IV)
  • For retainment with plan for eventual removal, treat with at least 2 weeks IV followed by oral suppression until hardware removal
  • Chronic suppressive antibiotics should be considered with difficult-to-treat organisms

Further Reading