Hemoglobin A1c: Difference between revisions
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$$ Avg Glucose \approx 1.59 \times HbA1c - 2.59 $$ |
$$ Avg Glucose \approx 1.59 \times HbA1c - 2.59 $$ |
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{| class="wikitable" |
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!HbA1c (%) |
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* Normal <5.7% |
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!Interpretation |
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* Elevated 5.7% to 6.4% |
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|- |
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* Diabetes ≥6.5% |
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|<5.5 |
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|normal |
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|- |
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|5.6 to 5.9 |
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|at risk |
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|- |
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|6 to 6.4 |
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|prediabetes |
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|- |
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|≥6.5 |
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|diabetes |
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|} |
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=== Falsely high === |
=== Falsely high === |
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Latest revision as of 18:48, 5 September 2021
Interpretation
- Approximates 90-day random blood glucose
$$ Avg Glucose \approx 1.59 \times HbA1c - 2.59 $$
| HbA1c (%) | Interpretation |
|---|---|
| <5.5 | normal |
| 5.6 to 5.9 | at risk |
| 6 to 6.4 | prediabetes |
| ≥6.5 | diabetes |
Falsely high
- It can be elevated in people whose red blood cells have a longer lifespan
- Vitamin B12 and iron deficiency
- Splenectomy
- Also laboratory artifact
- Aspirin
- Cigarette carboxyhemoglobin
- Hb S, G, D, C, and E
- Hypertriglyceridemia
- Hyperbilirubinemia
- Others
- Afro-Caribbeans (+0.4%)
- Chronic renal failure
Falsely low
- It can be decreased by anything that shortens the lifespan of red blood cells
- Hemolysis
- Blood loss
- Spherocytosis
- Thalassemia HbS
- Supplementation with erythropoietin
- Supplementation with iron or vitamin B12
- Also laboratory artifacts
- Sickle cell HbF
- Others
- Vitamin A or C supplementation
- HIV antiretrovials
- Chronic liver disease
- Chronic renal failure
Alternatives
- Fructosamine
- Self-monitored capillary blood glucose
