Campylobacter jejuni: Difference between revisions
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Campylobacter jejuni
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== Background == |
== Background == |
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=== Microbiology === |
=== Microbiology === |
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* Curved [[Stain::Gram-negative]] [[ |
* Curved [[Stain::Gram-negative]] [[Shape::bacillus]] |
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* Grows best at 42ºC (body temperature of birds) |
* Grows best at 42ºC (body temperature of birds) |
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* Exhibits darting motility |
* Exhibits darting motility |
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Revision as of 08:08, 9 October 2020
Background
Microbiology
- Curved Gram-negative bacillus
- Grows best at 42ºC (body temperature of birds)
- Exhibits darting motility
Epidemiology
- Major host is birds, including poultry
Clinical Manifestations
- Causes infectious diarrhea, including dysentery
Diagnosis
- Stool culture or PCR
Management
- Supportive care for the diarrhea
- Antibiotic choice depends on where the infection was acquired
- Ciprofloxacin 500 mg PO bid for 3 days is useful where there are relatively low rates of resistance (North American and Europe)
- Or other fluoroquinolone for 3 days
- Azithromycin 500 mg PO daily for 3 days is useful where there are higher rates of resistance (especially South and Southeast Asia)
- An alternative is rifaximin 200 mg PO tid for 3 days, but should be avoided in patients who have dysentery or fever
- Ciprofloxacin 500 mg PO bid for 3 days is useful where there are relatively low rates of resistance (North American and Europe)
Prognosis
- Usually a self-limited illness whose duration is shortened by antibiotics
- Can subsequently develop post-infectious irritable bowel syndrome
- Most common cause of Guillain-Barré syndrome
