Congenital parvovirus: Difference between revisions

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== Background ==
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{| class="wikitable"
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!Trimester
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!Transmission to Fetus
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|-
  +
|first
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| rowspan="2" |33%
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|-
  +
|second
  +
|-
  +
|third
  +
|0%
  +
|-
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|overall
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|9%
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|}
  +
  +
== Clinical Presentation ==
  +
  +
* Hydrops fetalis in utero
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* Heart failure
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* Myocarditis
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==Diagnosis==
 
==Diagnosis==
 
===Serology===
 
===Serology===
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* IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
 
* IgG antibody is detectable about 2 weeks after infection and persists for life
+
*IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
 
*IgG antibody is detectable about 2 weeks after infection and persists for life
   
 
{| class="wikitable"
 
{| class="wikitable"
! IgM !! IgG !! Interpretation
+
!IgM!!IgG!!Interpretation
 
|-
 
|-
| || || Susceptible
+
|−||−||Susceptible
 
|-
 
|-
| + || || Acute infection
+
| +||−||Acute infection
 
|-
 
|-
| || + || Remote infection, at least 3-4 months ago
+
|−||+||Remote infection, at least 3-4 months ago
 
|-
 
|-
| + || + || Recent infection, within 2-3 months
+
| +||+||Recent infection, within 2-3 months
 
|}
 
|}
   

Latest revision as of 20:18, 21 September 2020

Background

Trimester Transmission to Fetus
first 33%
second
third 0%
overall 9%

Clinical Presentation

  • Hydrops fetalis in utero
  • Heart failure
  • Myocarditis

Diagnosis

Serology

  • IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
  • IgG antibody is detectable about 2 weeks after infection and persists for life
IgM IgG Interpretation
Susceptible
+ Acute infection
+ Remote infection, at least 3-4 months ago
+ + Recent infection, within 2-3 months