Ebola virus: Difference between revisions

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== Microbiology ==
==Microbiology==


* Negative-sense single-stranded RNA virus in the Filoviridae family
*Negative-sense single-stranded RNA virus in the [[Filoviridae]] family
*The ebolavirus genus includes five species:
**Zaire ebolavirus (EBOV), the most common
**Bundibugyo ebolavirus (BDBV)
**Reston ebolavirus (RESTV)
**Sudan ebolavirus (SUDV)
**TaΓ― Forest (or Cote d'Ivoire) ebolavirus (TAFV)


== Clinical Manifestations ==
==Clinical Manifestations==


* Incubation period [[Incubation period range::2 to 21 days]] (generally [[Usual incubation period::3 to 13 days]])
*Incubation period [[Incubation period range::2 to 21 days]] (generally [[Usual incubation period::3 to 13 days]])
* Fever, fatigue, myalgias, weakness, and dizziness
*Fever, fatigue, myalgias, weakness, and dizziness
* EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
*EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
* Relapse can occur as uveitis or meningitis
*Relapse can occur as uveitis or meningitis

=== Prognosis and Complications ===

* 33 to 75% mortality, depending mostly on supportive care


[[Category:Filoviridae]]
[[Category:Filoviridae]]

Revision as of 13:15, 28 August 2020

Microbiology

  • Negative-sense single-stranded RNA virus in the Filoviridae family
  • The ebolavirus genus includes five species:
    • Zaire ebolavirus (EBOV), the most common
    • Bundibugyo ebolavirus (BDBV)
    • Reston ebolavirus (RESTV)
    • Sudan ebolavirus (SUDV)
    • TaΓ― Forest (or Cote d'Ivoire) ebolavirus (TAFV)

Clinical Manifestations

  • Incubation period 2 to 21 days (generally 3 to 13 days)
  • Fever, fatigue, myalgias, weakness, and dizziness
  • EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
  • Relapse can occur as uveitis or meningitis

Prognosis and Complications

  • 33 to 75% mortality, depending mostly on supportive care