Imipenem-relebactam: Difference between revisions
From IDWiki
No edit summary |
No edit summary |
||
| Line 10: | Line 10: | ||
*Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
*Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
||
*No activity against many Gram-positives or afermentative Gram-negatives |
*No activity against many Gram-positives or afermentative Gram-negatives |
||
[[Category:Carbapenems]] |
|||
[[Category:β-lactamase inhibitors]] |
|||
Latest revision as of 14:02, 26 August 2020
Background
Mechanism of Action
- Relebactam improves activity against beta-lactamases including class A and C
- Also includes cilastatin, as per usual with imipenem
Spectrum of Activity
- Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas
- No activity against many Gram-positives or afermentative Gram-negatives
