Imipenem-relebactam: Difference between revisions
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+ | ==Background== |
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+ | ===Mechanism of Action=== |
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+ | *Relebactam improves activity against beta-lactamases including class A and C |
| + | *Also includes cilastatin, as per usual with imipenem |
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+ | ===Spectrum of Activity=== |
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+ | *Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
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+ | *No activity against many Gram-positives or afermentative Gram-negatives |
Revision as of 10:01, 26 August 2020
Background
Mechanism of Action
- Relebactam improves activity against beta-lactamases including class A and C
- Also includes cilastatin, as per usual with imipenem
Spectrum of Activity
- Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas
- No activity against many Gram-positives or afermentative Gram-negatives
