Norovirus: Difference between revisions

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==Background==
==Background==
===Virology===
===Microbiology===


*Member of the ''[[Caliciviridae]]'' family of positive-sense single-stranded RNA viruses
*Member of the ''[[Caliciviridae]]'' family of positive-sense single-stranded RNA viruses

=== Epidemiology ===

* Most common cause of gastroenteritis worldwide
* More common during winder months
* Antibodies from prior infection do not indicate immunity from future infection


==Clinical Manifestations==
==Clinical Manifestations==


*Incubation period of [[Usual incubation period::24 to 48 hours]]
*Incubation period of [[Usual incubation period::24 to 48 hours]]
*Nausea and vomiting followed by profuse diarrhea
*Causes [[Causes::viral gastroenteritis]], with [[Causes::nausea]] and [[Causes::vomiting]] followed by profuse [[Causes::watery diarrhea]]
*Illness lasts 12 to 72 hours
*Illness lasts 12 to 72 hours
*May have low-grade fevers
*May have low-grade fevers

Revision as of 23:55, 22 August 2020

Background

Microbiology

  • Member of the Caliciviridae family of positive-sense single-stranded RNA viruses

Epidemiology

  • Most common cause of gastroenteritis worldwide
  • More common during winder months
  • Antibodies from prior infection do not indicate immunity from future infection

Clinical Manifestations

Management

  • Supportive care and appropriate isolation and outbreak management

Outbreak Management

Kaplan criteria

  • Identify outbreaks of gastroenteritis caused by norovirus without specific viral testing1
  • The criteria are:
    • Vomiting in more than half of affected patients
    • Mean or median incubation period between 24 and 48 hours
    • Mean or median duration of illness between 12 and 60 hours
    • No bacterial pathogen identified in stool

References

  1. ^  R. M. Turcios, M.-A. Widdowson, A. C. Sulka, P. S. Mead, R. I. Glass. Reevaluation of Epidemiological Criteria for Identifying Outbreaks of Acute Gastroenteritis Due to Norovirus: United States, 1998-2000. Clinical Infectious Diseases. 2006;42(7):964-969. doi:10.1086/500940.