Acyclovir: Difference between revisions
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Created page with "* Acyclic guanosine analog that competes with deoxyguanosine triphosphate to inhibit viral DNA polymerase * Resistance mediated by mutation in or decrease of thymidine kinase..." |
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*Acyclic guanosine analog that competes with deoxyguanosine triphosphate to inhibit viral DNA polymerase |
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*Resistance mediated by mutation in or decrease of thymidine kinase |
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*Adverse drug reactions include: |
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**[[Adverse drug reaction::Acute kidney injury]] from crystal deposition, so maintain hydration |
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** Phlebitis |
**[[Adverse drug reaction::Phlebitis]] |
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** Neurotoxicity, with lethargy, confusion, tremor, myoclonus, agitation, hallucinations, and extrapyramidal symptoms |
**[[Adverse drug reaction::Neurotoxicity]], with lethargy, confusion, tremor, myoclonus, agitation, hallucinations, and extrapyramidal symptoms |
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[[Category:Antivirals]] |
[[Category:Antivirals]] |
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Revision as of 14:02, 12 August 2020
- Acyclic guanosine analog that competes with deoxyguanosine triphosphate to inhibit viral DNA polymerase
- Resistance mediated by mutation in or decrease of thymidine kinase
- Adverse drug reactions include:
- Acute kidney injury from crystal deposition, so maintain hydration
- Phlebitis
- Neurotoxicity, with lethargy, confusion, tremor, myoclonus, agitation, hallucinations, and extrapyramidal symptoms
