Norovirus: Difference between revisions

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==Background==
==Background==
===Virology===
===Virology===

* Member of the ''Caliciviridae'' family of positive-sense single-stranded RNA viruses
*Member of the ''[[Caliciviridae]]'' family of positive-sense single-stranded RNA viruses


==Clinical Manifestations==
==Clinical Manifestations==

* Incubation period of [[Usual incubation period::24 to 48 hours]]
*Incubation period of [[Usual incubation period::24 to 48 hours]]
* Nausea and vomiting followed by profuse diarrhea
*Nausea and vomiting followed by profuse diarrhea
* Illness lasts 12 to 72 hours
*Illness lasts 12 to 72 hours
* May have low-grade fevers
*May have low-grade fevers


==Management==
==Management==

* Supportive care and appropriate isolation and outbreak management
*Supportive care and appropriate isolation and outbreak management


==Outbreak Management==
==Outbreak Management==
===Kaplan criteria===
===Kaplan criteria===

* Identify outbreaks of gastroenteritis caused by norovirus without specific viral testing[[CiteRef::turcios2006re]]
*Identify outbreaks of gastroenteritis caused by norovirus without specific viral testing[[CiteRef::turcios2006re]]
* The criteria are:
*The criteria are:
** Vomiting in more than half of affected patients
**Vomiting in more than half of affected patients
** Mean or median incubation period between 24 and 48 hours
** Mean or median duration of illness between 12 and 60 hours
**Mean or median incubation period between 24 and 48 hours
**Mean or median duration of illness between 12 and 60 hours
** No bacterial pathogen identified in stool
**No bacterial pathogen identified in stool


[[Category:RNA viruses]]
[[Category:RNA viruses]]

Revision as of 21:09, 10 August 2020

Background

Virology

  • Member of the Caliciviridae family of positive-sense single-stranded RNA viruses

Clinical Manifestations

  • Incubation period of 24 to 48 hours
  • Nausea and vomiting followed by profuse diarrhea
  • Illness lasts 12 to 72 hours
  • May have low-grade fevers

Management

  • Supportive care and appropriate isolation and outbreak management

Outbreak Management

Kaplan criteria

  • Identify outbreaks of gastroenteritis caused by norovirus without specific viral testing1
  • The criteria are:
    • Vomiting in more than half of affected patients
    • Mean or median incubation period between 24 and 48 hours
    • Mean or median duration of illness between 12 and 60 hours
    • No bacterial pathogen identified in stool

References

  1. ^  R. M. Turcios, M.-A. Widdowson, A. C. Sulka, P. S. Mead, R. I. Glass. Reevaluation of Epidemiological Criteria for Identifying Outbreaks of Acute Gastroenteritis Due to Norovirus: United States, 1998-2000. Clinical Infectious Diseases. 2006;42(7):964-969. doi:10.1086/500940.