Myeloproliferative disorders: Difference between revisions

Latest revision as of 12:17, 2 August 2020

Criterion	PV	ET	PMF
CBC	Hb >165 (men) or >160 (women) Hct >48% (men) or 49% (women) RBC mass >25% predicted	Plts ≥450	WBC ≥11 (minor) Anemia (minor)
Bone marrow	Panmyelosis	Megakeryocytosis	Megakaryocytosis ± fibrosis
JAK2	JAK2 or JAK2 exon 12	JAK2, CALR, or MPL	JAK2, CALR, or MPL
Other	Low serum epo (minor)	Not otherwise explained Clonal marker (minor) Not reactive thrombocytosis	Not otherwise explained Palpable spleen (minor) High LDH (minor)

@@ Line 1: / Line 1: @@
-== Criteria ==
+==Criteria==
+{| class="wikitable"
-{|
-! Criterion
+!Criterion
+![[Polycythemia vera|PV]]
-! PV
+![[Essential thrombocythemia|ET]]
-! ET
+![[Primary myelofibrosis|PMF]]
-! PMF
 |-
-| CBC
+|CBC
-| Hb &gt;165 (men) or &gt;160 (women)<br/>Hct &gt;48% (men) or 49% (women)<br/>RBC mass &gt;25% predicted
+|Hb &gt;165 (men) or &gt;160 (women)<br />Hct &gt;48% (men) or 49% (women)<br />RBC mass &gt;25% predicted
-| Plts ≥450
+|Plts ≥450
-| WBC ≥11 (minor)<br/>Anemia (minor)
+|WBC ≥11 (minor)<br />Anemia (minor)
 |-
-| Bone marrow
+|Bone marrow
-| Panmyelosis
+|Panmyelosis
-| Megakeryocytosis
+|Megakeryocytosis
-| Megakaryocytosis ± fibrosis
+|Megakaryocytosis ± fibrosis
 |-
-| JAK2
+|JAK2
-| JAK2 or JAK2 exon 12
+|JAK2 or JAK2 exon 12
-| JAK2, CALR, or MPL
+|JAK2, CALR, or MPL
-| JAK2, CALR, or MPL
+|JAK2, CALR, or MPL
 |-
-| Other
+|Other
-| Low serum epo (minor)
+|Low serum epo (minor)
-| Not otherwise explained<br/>Clonal marker (minor)<br/>Not reactive thrombocytosis
+|Not otherwise explained<br />Clonal marker (minor)<br />Not reactive thrombocytosis
-| Not otherwise explained<br/>Palpable spleen (minor)<br/>High LDH (minor)
+|Not otherwise explained<br />Palpable spleen (minor)<br />High LDH (minor)
 |}