Prosthetic joint infection: Difference between revisions
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[[Category:Bone and joint infections]] |
[[Category:Bone and joint infections]] |
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[[Category:Infectious diseases]] |
[[Category:Infectious diseases]] |
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== Background == |
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=== Microbiology === |
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* Hip and knee |
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** Early (<3 months): [[Staphylococcus aureus]] (38%), aerobic [[Gram-negative bacilli]] (24%), [[coagulase-negative staphylococci]] (22%), [[Enterococcus species]] (10%), and [[Streptococcus species]] (4%), [[anaerobes]] including [[Cutibacterium acnes]] (3%), culture-negative (10%); 31% are polymicrobial |
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** Overall: [[Staphylococcus aureus]] (27%), [[coagulase-negative staphylococci]] (27%), aerobic [[Gram-negative bacilli]] (9%), [[Streptococcus species]] (8%), [[anaerobes]] including [[Cutibacterium acnes]] (4%), [[Enterococcus species]] (3%), culture-negative (14%); 15% are polymicrobial |
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* Shoulder: [[coagulase-negative staphylococci]] (42%), [[Cutibacterium acnes]] (24%), [[Staphylococcus aureus]] (18%), aerobic [[Gram-negative bacilli]] (10%), others, culture-negative (15%); polymicrobial in 16% |
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* Elbow: [[Staphylococcus aureus]] (42%), [[coagulase-negative staphylococci]] (41%), others, culture-negative (5%); polymicrobial in 3% |
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=== Epidemiology === |
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* Complicates about 2% of [[arthroplasty]] |
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=== Pathophysiology === |
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* Bacteria grown on the prosthesis in a biofilm, making it resistant to medical management |
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== Further Reading == |
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* Prosthetic Joint Infection. ''Clin Micro Rev''. 2014;27(2):302-345. doi: [https://doi.org/10.1128/CMR.00111-13 10.1128/CMR.00111-13] |
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Revision as of 23:52, 8 July 2020
Background
Microbiology
- Hip and knee
- Early (<3 months): Staphylococcus aureus (38%), aerobic Gram-negative bacilli (24%), coagulase-negative staphylococci (22%), Enterococcus species (10%), and Streptococcus species (4%), anaerobes including Cutibacterium acnes (3%), culture-negative (10%); 31% are polymicrobial
- Overall: Staphylococcus aureus (27%), coagulase-negative staphylococci (27%), aerobic Gram-negative bacilli (9%), Streptococcus species (8%), anaerobes including Cutibacterium acnes (4%), Enterococcus species (3%), culture-negative (14%); 15% are polymicrobial
- Shoulder: coagulase-negative staphylococci (42%), Cutibacterium acnes (24%), Staphylococcus aureus (18%), aerobic Gram-negative bacilli (10%), others, culture-negative (15%); polymicrobial in 16%
- Elbow: Staphylococcus aureus (42%), coagulase-negative staphylococci (41%), others, culture-negative (5%); polymicrobial in 3%
Epidemiology
- Complicates about 2% of arthroplasty
Pathophysiology
- Bacteria grown on the prosthesis in a biofilm, making it resistant to medical management
Further Reading
- Prosthetic Joint Infection. Clin Micro Rev. 2014;27(2):302-345. doi: 10.1128/CMR.00111-13
