Escherichia coli: Difference between revisions

Revision as of 14:41, 5 December 2019

Background

Microbiology

Lactose-fermenting Gram-negative bacillus within the Enterobacteriaceae
Member of commensal gut flora

Classification

Has multiple pathotypes
- Extraintestinal pathogenic E. coli (ExPEC): causes UTI and neonatal meningitis
  - Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
- Enteropathogenic E. coli (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
- Enterotoxigenic E. coli (ETEC): produces enterotoxins, causes acute watery diarrhea
- Enterhemorrhagic E.coli (EHEC) and Shiga toxin-producing E. coli (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
- Enteroaggregative E. coli (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
- Enteroinvasive E. coli (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
- Diffuse-adhering E. coli (DAEC): causes diarrhea

@@ Line 3: / Line 3: @@
 * Lactose-fermenting [[Has Gram stain::Gram-negative]] [[Has shape::bacillus]] within the [[Enterobacteriaceae]]
 * Member of commensal gut flora
+=== Classification ===
 * Has multiple '''pathotypes'''
-** Extraintestinal pathogenic ''E. coli'' (ExPEC): causes UTI and neonatal meningitis
+** '''Extraintestinal pathogenic ''E. coli'' (ExPEC):''' causes UTI and neonatal meningitis
 *** Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
-** Enterotoxigenic ''E. coli'' (ETEC): produces enterotoxins, causes acute watery diarrhea
+** '''Enteropathogenic ''E. coli'' (EPEC):''' produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
-** Enteropathogenic ''E. coli'' (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
+** '''Enterotoxigenic ''E. coli'' (ETEC):''' produces enterotoxins, causes acute watery diarrhea
-** Enterhemorrhagic ''E.coli'' (EHEC) and Shiga toxin-producing ''E. coli'' (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
+** '''Enterhemorrhagic ''E.coli'' (EHEC) and Shiga toxin-producing ''E. coli'' (STEC):''' produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
-** Enteroaggregative ''E. coli'' (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
+** '''Enteroaggregative ''E. coli'' (EAEC):''' produces adherence factors, causes mucoid diarrhea that can become chronic
-** Enteroinvasive ''E. coli'' (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
+** '''Enteroinvasive ''E. coli'' (EIEC):''' spreads cell-to-cell, causes watery diarrhea or dysentery
-** Diffuse-adhering ''E. coli'' (DAEC): causes diarrhea
+** '''Diffuse-adhering ''E. coli'' (DAEC):''' causes diarrhea
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