Mycetoma: Difference between revisions
From IDWiki
(Initial page creation) |
m (added category) |
||
| Line 29: | Line 29: | ||
* Send granules in sterile container |
* Send granules in sterile container |
||
* Gram stain a crushed granule for bacteria, then set up cultures for bacterial and fungal cultures |
* Gram stain a crushed granule for bacteria, then set up cultures for bacterial and fungal cultures |
||
[[Category:Skin and soft tissue infections]] |
|||
Revision as of 19:55, 2 November 2019
- Chronic progressive granulomatous infection of the skin and subcutaneous tissue, usually affecting a single extremity
Background
Microbiology
- Can be caused either by fungi or filamentous aerobic bacteria
- Fungal species (eumycotic mycetoma):
- Dark grains:
- Pale/white grains:
- Pseudallescheria boydii (most common) (Scedosporium)
- Acremonium kiliense
- Aspergillus flavus, Aspergillus nidulans, Aspergillus hollandicus
- Aerobic bacteria (actinomycotic mycetoma):
- Nocardia brasiliensis
- Actinomadura madurae
- Streptomyces somaliensis
- Actinomadura pelletieri (grains are red to pink)
Clinical Presentation
- Clinical triad:
- Localized swelling
- Underlying sinus tract
- Grains and granules (“sulfur granules”) within the sinus tracts
Diagnosis
- Send granules in sterile container
- Gram stain a crushed granule for bacteria, then set up cultures for bacterial and fungal cultures
References
- ^ Wendy W. J. van de Sande, Ahmed H. Fahal. Graeme N. Forrest. An updated list of eumycetoma causative agents and their differences in grain formation and treatment response. Clinical Microbiology Reviews. 2024;37(2). doi:10.1128/cmr.00034-23.
- ^ Wendy W. J. van de Sande, Ahmed H. Fahal, Michael Goodfellow, El Sheikh Mahgoub, Oliverio Welsh, Ed E. Zijlstra. Todd Reynolds. Merits and Pitfalls of Currently Used Diagnostic Tools in Mycetoma. PLoS Neglected Tropical Diseases. 2014;8(7):e2918. doi:10.1371/journal.pntd.0002918.
