SPICE organisms: Difference between revisions
From IDWiki
No edit summary |
(→: linkified) |
||
| Line 5: | Line 5: | ||
== Organisms == |
== Organisms == |
||
| − | * |
+ | * [[Serratia species]] |
| − | * |
+ | * [[Providencia]] |
| − | * Indole-positive |
+ | * Indole-positive [[Proteus species]] (e.g. [[Proteus vulgaris]], but not [[Proteus mirabilis]]) |
| − | * |
+ | * [[Citrobacter species]] |
| − | ** |
+ | ** [[C. koseri]] does ''not'' have an AmpC |
| − | * |
+ | * [[Enterobacter cloacae]] |
Also: |
Also: |
||
| − | * |
+ | * [[Hafnia alvei]] |
| − | * |
+ | * [[Acinetobacter]], though not inducible or AmpC (merely very resistant_ |
| − | * |
+ | * [[Morganella morganii]] |
| − | * |
+ | * [[Cronobacter]] |
| − | * |
+ | * [[Edwardsiella]] |
== Treatment == |
== Treatment == |
||
Revision as of 16:33, 28 September 2019
Definition
- Gram-negative bacteria with inducible or derepressable beta-lactamases, primarily chromosomal AmpC
Organisms
- Serratia species
- Providencia
- Indole-positive Proteus species (e.g. Proteus vulgaris, but not Proteus mirabilis)
- Citrobacter species
- C. koseri does not have an AmpC
- Enterobacter cloacae
Also:
- Hafnia alvei
- Acinetobacter, though not inducible or AmpC (merely very resistant_
- Morganella morganii
- Cronobacter
- Edwardsiella
Treatment
- Not penicillins or cephalosporins, as resistance will develop within a few days
- Carbapenems still work, as do aminoglycosides
Further Reading
- Jones R, Baquero F, Privitera G, Inoue M, Widermann B. Inducible β-lactamase-mediated resistance to third-generation cephalosporins. Clin Microbio Infect. 1997;3(1):S7-S20.
- https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciz173/5369903
