Trypanosoma: Difference between revisions
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Trypanosoma
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= ''Trypanosoma'' spp. = |
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== Microbiology == |
== Microbiology == |
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** ''T. brucei gambiense'' and ''T. brucei rhodesiense'', which cause African sleeping sickness |
** ''T. brucei gambiense'' and ''T. brucei rhodesiense'', which cause African sleeping sickness |
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** Something else? |
** Something else? |
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{{DISPLAYTITLE:''Trypanosoma'' species}} |
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[[Category:Parasites]] |
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Revision as of 12:21, 16 August 2019
Microbiology
- Flagellated vector-borne protozoan parasite of mammals in the genus Trypanosoma
- Generally have three morphological states: epimastigote, amastigote, and trypomastigote
- T. cruzi has an intracellular amastigote while T. brucei do not, but rather multiply as trypomastigotes in the bloodstream
- Amastigotes are commonly intracellular, and are small with a very short flagellum
- Epimastigotes have a flagellum that runs along and connects as an undulating membrane, with the kinetoplast anterior to the nucleus
- Trypomastigotes have a similar flagellum as epimastigotes, but with the kinetoplast posterior to the nucleus
- Two major groups
- Stercoraria, which multiply discontinuously in the mammal as amastigotes, and develop in the vector in the hindgut
- Transferred via contaminated feces
- e.g. T. cruzi
- Salivaria, which multiply continuously in the mammal as trypomastigotes, and develop in the vector in the salivary glands
- Transferred via saliva
- e.g. T. brucei
- Stercoraria, which multiply discontinuously in the mammal as amastigotes, and develop in the vector in the hindgut
- Three species infect humans
- T. cruzi, which causes Chagas disease
- T. brucei gambiense and T. brucei rhodesiense, which cause African sleeping sickness
- Something else?
