Actinomyces: Difference between revisions
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Actinomyces
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== Management == |
== Management == |
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* IV penicillin x4-6 weeks then PO penicillin x6-12 months |
* IV [[penicillin]] x4-6 weeks then PO [[penicillin]] x6-12 months |
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* Alternatives include ceftriaxone, amox/clav |
* Alternatives include [[ceftriaxone]], amox/clav |
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{{DISPLAYTITLE:''Actinomyces'' species}} |
{{DISPLAYTITLE:''Actinomyces'' species}} |
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Revision as of 12:11, 16 August 2019
Microbiology
- Weakly Gram-positive bacterium that looks fungal under microscopy
- Oral and gut flora
- Spreads by direct invasion through tissue and creating fistulae
Syndromes
Cervicofacial actinomycosis
- "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
- Most common form, accounting for ~50% of cases
Abdominal actinomycosis
- Presents as an abdominal mass that fistulizes to skin
Pulmonary actinomycosis
- Presents as a chronic, non-resolving pneumonia or as a lung cancer
- Can spread directly to involve heart as well
Others
- Endocarditis
Management
- IV penicillin x4-6 weeks then PO penicillin x6-12 months
- Alternatives include ceftriaxone, amox/clav
References
- ^ Anna Jeffery-Smith, Caoimhe Nic-Fhogartaigh, Michael Millar. P. Bourbeau. Is the Presence of Actinomyces spp. in Blood Culture Always Significant?. Journal of Clinical Microbiology. 2016;54(4):1137-1139. doi:10.1128/jcm.03074-15.