Vibrio parahaemolyticus: Difference between revisions

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Vibrio parahaemolyticus
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== Microbiology ==
== Microbiology ==


- Halophilic (salt-loving) marine pleomorphic Gram-negative rod that causes foodborne diarrhea
* Halophilic (salt-loving) marine pleomorphic Gram-negative rod that causes foodborne diarrhea


== Pathophysiology ==
== Pathophysiology ==
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== Epidemiology ==
== Epidemiology ==


- Major cause of acute diarrhea in Japan, but also found in east Asia and southern US
* Major cause of acute diarrhea in Japan, but also found in east Asia and southern US
- Ubiquitous in coastal waters, especially in warmer seasons
* Ubiquitous in coastal waters, especially in warmer seasons
- Generally acquired by consumption of raw or undercooked seafood, especially raw oysters
* Generally acquired by consumption of raw or undercooked seafood, especially raw oysters
- Serotype O3:K6 is an important cause of outbreaks, and is the current pandemic strain
* Serotype O3:K6 is an important cause of outbreaks, and is the current pandemic strain


== Clinical Presentation ==
== Clinical Presentation ==


- Causes acute diarrhea, ranging from mild watery diarrhea to dysentery
* Causes acute diarrhea, ranging from mild watery diarrhea to dysentery
- Usually, cramping and abdominal pain with low-grade fever and headache
* Usually, cramping and abdominal pain with low-grade fever and headache
- Rarely can cause soft tissue infections and bacteremia
* Rarely can cause soft tissue infections and bacteremia


== Management ==
== Management ==


- Usually self-limited
* Usually self-limited
- Can use doxycycline or fluoroquinolone to shorten the duration of diarrhea
* Can use [[doxycycline]] or [[fluoroquinolone]] to shorten the duration of diarrhea


{{DISPLAYTITLE:''Vibrio parahaemolyticus''}}
{{DISPLAYTITLE:''Vibrio parahaemolyticus''}}

Revision as of 12:02, 16 August 2019

Microbiology

  • Halophilic (salt-loving) marine pleomorphic Gram-negative rod that causes foodborne diarrhea

Pathophysiology

  • Has the capacity to produce an enterotoxin that causes small bowel inflammation
    • Two hemolysins, thermostable direct hemolysin (TDH) and TGH-related hemolysin (TRH)
  • Strains without TDH or TRH are usually mild
  • Likely has a different mechanism of action thatn *V. cholera* for causing diarrhea

Epidemiology

  • Major cause of acute diarrhea in Japan, but also found in east Asia and southern US
  • Ubiquitous in coastal waters, especially in warmer seasons
  • Generally acquired by consumption of raw or undercooked seafood, especially raw oysters
  • Serotype O3:K6 is an important cause of outbreaks, and is the current pandemic strain

Clinical Presentation

  • Causes acute diarrhea, ranging from mild watery diarrhea to dysentery
  • Usually, cramping and abdominal pain with low-grade fever and headache
  • Rarely can cause soft tissue infections and bacteremia

Management