Fluconazole: Difference between revisions
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= Fluconazole = |
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== Classification == |
== Classification == |
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** EKG (QT prolongation) |
** EKG (QT prolongation) |
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* Beware drug-drug interactions, especially with new DOACs |
* Beware drug-drug interactions, especially with new DOACs |
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[[Category:Antifungals]] |
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Revision as of 20:04, 15 August 2019
Classification
- Antifungal in the triazole family with excellent bioavadilability but limited efficacy outside of Candida
Indications
- Fungal infections
Monitoring
- ECG for QT prolongation
- Liver enzymes for hepatitis
Pharmacokinetics
- Good oral bioavailability
- CNS penetration
Side Effects
- Best side effect profiles of the antifungals
- Before starting, check:
- Liver enzymes as baseline
- Creatinine (requires renal dosing)
- EKG (QT prolongation)
- Beware drug-drug interactions, especially with new DOACs
