Imipenem-cilastatin: Difference between revisions
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Created page with "== Background == * Broad-spectrum carbapenem * Spectrum includes enterococci and Acinetobacter ** Compared to meropenem, imipenem is more active against Acinetobacter and enterococci, and less active against Pseudomonas == Dosing == * Routine: 500 mg IV every 6 hours * Cystitis: 250-500 mg IV every 6 hours * Severe or pseudomonal infections: consider up to 1 g IV every 6 to 8 hours Category:Carbapenems" |
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* Broad-spectrum carbapenem |
* Broad-spectrum carbapenem |
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* Spectrum includes [[enterococci]] and [[Acinetobacter]] |
* Spectrum includes [[enterococci]] and [[Acinetobacter]] |
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** Compared to [[meropenem]], imipenem is more active against [[Acinetobacter]] and [[enterococci]], and less active against [[Pseudomonas]] |
** Compared to [[meropenem]], imipenem is more active against [[Acinetobacter]] and [[enterococci]], and possibly less active against [[Pseudomonas]] |
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== Dosing == |
== Dosing == |
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Latest revision as of 14:47, 14 November 2025
Background
- Broad-spectrum carbapenem
- Spectrum includes enterococci and Acinetobacter
- Compared to meropenem, imipenem is more active against Acinetobacter and enterococci, and possibly less active against Pseudomonas
Dosing
- Routine: 500 mg IV every 6 hours
- Cystitis: 250-500 mg IV every 6 hours
- Severe or pseudomonal infections: consider up to 1 g IV every 6 to 8 hours