Coagulase-negative staphylococci: Difference between revisions
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* Common [[Blood culture contamination|contaminants of blood culture bottles]] |
* Common [[Blood culture contamination|contaminants of blood culture bottles]] |
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* Infections more commonly of indwelling hardware |
* Infections more commonly of indwelling hardware |
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* Endocarditis occasionally, and the highest risk is with [[Staphylococcus epidermidis]] than with other species[[CiteRef::ramos-martínez2023ri]] |
* Endocarditis occasionally, and the highest risk is with [[Staphylococcus epidermidis]] than with other species[[CiteRef::ramos-martínez2023ri]][[CiteRef::haddad2023bl]] |
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==Management== |
==Management== |
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Latest revision as of 18:18, 30 June 2025
- Group of Gram-positive cocci that are catalase positive and coagulase negative
Organisms
- Staphylococcus epidermidis group
- Staphylococcus haemolyticus group
- Staphylococcus saprophyticus: mainly causes UTIs
- Staphylococcus massiliensis
- Staphylococcus lugdenensis: has more in common with Staphylococcus aureus and should never be considered a contaminant
- Unclear grouping
Clinical Manifestations
- Common contaminants of blood culture bottles
- Infections more commonly of indwelling hardware
- Endocarditis occasionally, and the highest risk is with Staphylococcus epidermidis than with other species12
Management
- Generally resistant to β-lactams
- First-line: vancomycin
- Alternatives: linezolid, daptomycin, co-trimoxazole, ciprofloxacin, doxycycline
References
- ^ Antonio Ramos-Martínez, Patricia González-Merino, Elena Suanzes-Martín, Marta Murga-de la Fuente, Gabriela Escudero-López, Ane Andrés-Eisenhofer, Esther Expósito-Palomo, Andrea Gutierrez-Villanueva, Itziar Diego-Yagüe, Elena Múñez, Ana Fernandez-Cruz, Jorge Calderón-Parra. Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia. Scientific Reports. 2023;13(1). doi:10.1038/s41598-023-41888-7.
- ^ Sara F. Haddad, Brian D. Lahr, Sebastian Santos Patarroyo, Supavit Chesdachai, Kami D. Kies, John C. O’Horo, Daniel C. DeSimone, Parham Sendi, Larry M. Baddour. Bloodstream Infection Due to Coagulase-Negative Staphylococci: Impact of Species on Prevalence of Infective Endocarditis. Antibiotics. 2023;12(9):1453. doi:10.3390/antibiotics12091453.
