Roseolavirus: Difference between revisions
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== Background == |
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=== Microbiology === |
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* Includes HHV-6A, HHV-6B, and HHV-7 |
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* Group of viruses that includes HHV-6B (most common cause), as well as HHV-6A and HHV-7 (less common cause) |
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=== Epidemiology === |
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* Most commonly infects children between 6 months and 2 years of age |
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* Transmission likely from asymptomatic shedding in saliva |
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== Clinical Manifestations == |
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* Causes roseola infantum, also known as '''exanthem subitum''' or '''sixth disease''' |
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* Fever can be high-grade and typically lasts 3 to 5 days, followed by defervescence and appearance of rash |
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* Rash is typically '''rose-pink''', discrete circular or elliptical macular or maculopapular lesions measuring 2 to 5 mm |
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** Blanchable |
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** Starts on trunk and spreads to neck and proximal extremities |
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** Lasts 2 to 4 days |
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* Children generally otherwise appear well |
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* Can cause [[febrile seizure]] |
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== Diagnosis == |
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* Diagnosis is made clinically |
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== Management == |
== Management == |
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* Case reports exist of treating HHV-6 meningitis with ganciclovir or foscarnet |
* Case reports exist of treating HHV-6 meningitis with [[ganciclovir]] or [[foscarnet]] |
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[[Category:Herpesviridae]] |
[[Category:Herpesviridae]] |
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Latest revision as of 20:10, 16 June 2025
Background
Microbiology
- Group of viruses that includes HHV-6B (most common cause), as well as HHV-6A and HHV-7 (less common cause)
Epidemiology
- Most commonly infects children between 6 months and 2 years of age
- Transmission likely from asymptomatic shedding in saliva
Clinical Manifestations
- Causes roseola infantum, also known as exanthem subitum or sixth disease
- Fever can be high-grade and typically lasts 3 to 5 days, followed by defervescence and appearance of rash
- Rash is typically rose-pink, discrete circular or elliptical macular or maculopapular lesions measuring 2 to 5 mm
- Blanchable
- Starts on trunk and spreads to neck and proximal extremities
- Lasts 2 to 4 days
- Children generally otherwise appear well
- Can cause febrile seizure
Diagnosis
- Diagnosis is made clinically
Management
- Case reports exist of treating HHV-6 meningitis with ganciclovir or foscarnet
