Doxycycline: Difference between revisions
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== Background == |
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* Tetracycline antibiotic |
* Tetracycline antibiotic |
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=== Spectrum of Activity === |
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=== Distribution === |
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* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this<ref>Tomasz Jodlowski, Charles R Ashby, Sarath G Nath, Doxycycline for ESBL-E Cystitis, ''Clinical Infectious Diseases'', Volume 73, Issue 1, 1 July 2021, Pages e274–e275, https://doi.org/10.1093/cid/ciaa1898</ref> |
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== Dosing == |
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* Usual dosing 100 mg po BID |
* Usual dosing 100 mg po BID |
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== Safety == |
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=== Adverse Effects === |
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* Counsel on high risk of sun sensitivity and pill esophagitis |
* Counsel on high risk of sun sensitivity and pill esophagitis |
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* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining |
* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining |
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** However, can often tolerate short courses up to 5 days without issue |
** However, can often tolerate short courses up to 5 days without issue |
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* Achieves only low concentrations in the urine, so generally not recommended for UTIs |
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[[Category:Tetracyclines]] |
[[Category:Tetracyclines]] |
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Revision as of 14:56, 1 November 2023
Background
- Tetracycline antibiotic
Spectrum of Activity
- Can treat: Actinomyces, Bacillary angiomatosis, Bartonella henselae, Borrelia miyamotoi, Brucella melitensis, Burkholderia mallei, Chlamydia trachomatis, Cutibacterium acnes, Enterococcus, Francisella tularensis, Legionella, Leptospira, Lymphogranuloma venereum, Mycoplasma genitalium, Pelvic inflammatory disease, Plasmodium, Rickettsia, Rickettsia africae, Rickettsia akari, Rickettsia conorii, Rickettsia prowazekii, Rickettsia rickettsii, Rickettsia typhi, Rickettsioses, Rickettsioses, Southern tick-associated rash illness, Stenotrophomonas maltophilia, Tick-borne relapsing fever, Treponema pallidum pallidum, Yersinia enterocolitica, Yersinia pestis
Distribution
- Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[1]
Dosing
- Usual dosing 100 mg po BID
Safety
Adverse Effects
- Counsel on high risk of sun sensitivity and pill esophagitis
- Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
- However, can often tolerate short courses up to 5 days without issue
- ↑ Tomasz Jodlowski, Charles R Ashby, Sarath G Nath, Doxycycline for ESBL-E Cystitis, Clinical Infectious Diseases, Volume 73, Issue 1, 1 July 2021, Pages e274–e275, https://doi.org/10.1093/cid/ciaa1898
