Single-tablet regimens for HIV: Difference between revisions

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[[Category:HIV]]
[[Category:HIV]]
[[Category:Antivirals]]

Revision as of 11:17, 16 August 2019

See also HIV treatment

Brand name NRTIs Non-NRTI Notes
Triumeq abacavir / lamivudine dolutegravir (INI) Highest barrier to resistance. Need to test for HLA-B5701 allele before starting. Avoid in hepatitis B coinfection.
Atripla tenofovir disoproxil / emtricitabine efavirenz Older regimen. Neuropsychiatric symptoms, possibly including suicide.
Complera tenofovir disoproxil / emtricitabine rilpivirine Avoid with viral loads (>100,000) or low CD4 (<200). Pill must be taken with food (>400kcal) and without PPIs.
Stribild tenofovir disoproxil / emtricitabine elvitegravir/cobicistat (INI) Includes a P450 inhibitor to boost elvitegravir levels, with resultant drug-drug interactions. Avoid if CrCl <70.
Biktarvy FTC/TAF BIC