Tuberculous adenitis: Difference between revisions
From IDWiki
Content deleted Content added
Created page with "== Clinical Manifestations == === Paradoxical Reactions === * Paradoxial reaction including paradoxical upgrading reaction * Occurs in 25% of adenitis ** Usually during trea..." |
No edit summary |
||
| Line 1: | Line 1: | ||
== |
==Clinical Manifestations== |
||
=== |
===Paradoxical Reactions=== |
||
* |
*Paradoxial reaction including paradoxical upgrading reaction |
||
*Presents with enlarging lymphadenopathy during or sometimes after treatment |
|||
* |
*Occurs in 25% of adenitis |
||
** Usually during treatment but can occur after treatment |
|||
* |
*Likely represents a reaction to an antigenic stimulus in poorly-cleared disease |
||
* |
*In post-treatment paradoxical reactions, need to differentiate from relapse |
||
* |
*About half will be PCR positive, 20% will be AFB positive, but none are culture positive |
||
*90% resolve spontaneously |
|||
*Steroids used commonly |
|||
[[Category:Tuberculosis]] |
[[Category:Tuberculosis]] |
||
Revision as of 13:44, 25 November 2020
Clinical Manifestations
Paradoxical Reactions
- Paradoxial reaction including paradoxical upgrading reaction
- Presents with enlarging lymphadenopathy during or sometimes after treatment
- Occurs in 25% of adenitis
- Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
- In post-treatment paradoxical reactions, need to differentiate from relapse
- About half will be PCR positive, 20% will be AFB positive, but none are culture positive
- 90% resolve spontaneously
- Steroids used commonly
References
- ^ C. R. Hawkey, T. Yap, J. Pereira, D. A. J. Moore, R. N. Davidson, G. Pasvol, O. M. Kon, R. A. Wall, R. J. Wilkinson. Characterization and Management of Paradoxical Upgrading Reactions in HIV-Uninfected Patients with Lymph Node Tuberculosis. Clinical Infectious Diseases. 2005;40(9):1368-1371. doi:10.1086/429317.
- ^ JH van Loenhout-Rooyackers, RJ Laheij, C Richter, AL Verbeek. Shortening the duration of treatment for cervical tuberculous lymphadenitis. European Respiratory Journal. 2000;15(1):192-195. doi:10.1183/09031936.00.15119200.
