Osteomyelitis: Difference between revisions

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* See also:
*See also:
** [[Acute osteomyelitis]]
**[[Acute osteomyelitis]]
** [[Chronic osteomyelitis]]
**[[Chronic osteomyelitis]]


== Management ==
==Management==


* No clinically meaningful differences in bone penetration between classes of antibiotics exist[[CiteRef::landersdorfer2009pe]]
*No clinically meaningful differences in bone penetration between classes of antibiotics exist[[CiteRef::landersdorfer2009pe]]
* Bioavailability still important
*Bioavailability likely still important


[[Category:Bone and joint infections]]
[[Category:Bone and joint infections]]

Revision as of 18:44, 18 September 2020

Management

  • No clinically meaningful differences in bone penetration between classes of antibiotics exist1
  • Bioavailability likely still important

References

  1. ^  Elysia A. Masters, Benjamin F. Ricciardi, Karen L. de Mesy Bentley, T. Fintan Moriarty, Edward M. Schwarz, Gowrishankar Muthukrishnan. Skeletal infections: microbial pathogenesis, immunity and clinical management. Nature Reviews Microbiology. 2022. doi:10.1038/s41579-022-00686-0.
  2. ^  Cornelia B. Landersdorfer, Jürgen B. Bulitta, Martina Kinzig, Ulrike Holzgrabe, Fritz Sörgel. Penetration of Antibacterials into Bone. Clinical Pharmacokinetics. 2009;48(2):89-124. doi:10.2165/00003088-200948020-00002.