Posaconazole: Difference between revisions
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==Therapeutic Drug Monitoring== |
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=== Epidemiologic Cutoff Values === |
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{| class="wikitable" |
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!Species |
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!ECV (mcg/mL) |
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|C. albicans |
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|0.06 |
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|C. glabrata |
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|2 |
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|C. parapsilosis |
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|0.25 |
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|C. tropicalis |
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|0.12 |
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|C. krusei |
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|0.5 |
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|C. lusitaniae |
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|0.12 |
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|C. guilliermondii |
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|0.5 |
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|C. kefyr |
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|0.25 |
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|} |
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[[Category:Triazoles]] |
[[Category:Triazoles]] |
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Revision as of 16:00, 19 January 2021
Therapeutic Drug Monitoring
- Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption
- For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
- For treatment, target trough >1 mg/L
Epidemiologic Cutoff Values
| Species | ECV (mcg/mL) |
|---|---|
| C. albicans | 0.06 |
| C. glabrata | 2 |
| C. parapsilosis | 0.25 |
| C. tropicalis | 0.12 |
| C. krusei | 0.5 |
| C. lusitaniae | 0.12 |
| C. guilliermondii | 0.5 |
| C. kefyr | 0.25 |
