Ebola virus: Difference between revisions

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== Microbiology ==
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==Microbiology==
   
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* Negative-sense single-stranded RNA virus in the Filoviridae family
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*Negative-sense single-stranded RNA virus in the [[Filoviridae]] family
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*The ebolavirus genus includes five species:
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**Zaire ebolavirus (EBOV), the most common
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**Bundibugyo ebolavirus (BDBV)
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**Reston ebolavirus (RESTV)
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**Sudan ebolavirus (SUDV)
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**TaΓ― Forest (or Cote d'Ivoire) ebolavirus (TAFV)
   
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== Clinical Manifestations ==
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==Clinical Manifestations==
   
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* Incubation period [[Incubation period range::2 to 21 days]] (generally [[Usual incubation period::3 to 13 days]])
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*Incubation period [[Incubation period range::2 to 21 days]] (generally [[Usual incubation period::3 to 13 days]])
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* Fever, fatigue, myalgias, weakness, and dizziness
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*Fever, fatigue, myalgias, weakness, and dizziness
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* EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
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*EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
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* Relapse can occur as uveitis or meningitis
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*Relapse can occur as uveitis or meningitis
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=== Prognosis and Complications ===
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* 33 to 75% mortality, depending mostly on supportive care
   
 
[[Category:Filoviridae]]
 
[[Category:Filoviridae]]

Revision as of 09:15, 28 August 2020

Microbiology

  • Negative-sense single-stranded RNA virus in the Filoviridae family
  • The ebolavirus genus includes five species:
    • Zaire ebolavirus (EBOV), the most common
    • Bundibugyo ebolavirus (BDBV)
    • Reston ebolavirus (RESTV)
    • Sudan ebolavirus (SUDV)
    • TaΓ― Forest (or Cote d'Ivoire) ebolavirus (TAFV)

Clinical Manifestations

  • Incubation period 2 to 21 days (generally 3 to 13 days)
  • Fever, fatigue, myalgias, weakness, and dizziness
  • EBOV can persist after resolution of symptoms in privileged sites: the eyes, CNS, male reproductive tract, and mammary glands
  • Relapse can occur as uveitis or meningitis

Prognosis and Complications

  • 33 to 75% mortality, depending mostly on supportive care