Neisseria meningitidis: Difference between revisions

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Neisseria meningitidis
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[[Category:Infectious diseases]]
 
[[Category:Infectious diseases]]
   
== Background ==
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==Background==
   
=== Microbiology ===
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===Microbiology===
   
* [[Gram stain::Gram-negative]] [[Cell shape::coccus|diplococcus]]
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*[[Gram stain::Gram-negative]] [[Cell shape::coccus|diplococcus]]
* Traditionally organized by serotyping of capsular polysaccharide
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*Traditionally organized by serogroups of capsular polysaccharide
** A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically
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**A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically
   
=== Epidemiology ===
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===Epidemiology===
   
* Six serogroups cause essentially all disease: A, B, C, W, X, and Y
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*Six serogroups cause essentially all disease: A, B, C, W, X, and Y
* In Canada, B, C, W-135 and Y are the most common causes, with B being the most commonly reported
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*In Canada, serogroups B, C, W-135 and Y are the most common causes, with B being the most commonly reported
** Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks
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**Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks

Revision as of 12:40, 31 July 2020


Background

Microbiology

  • Gram-negative diplococcus
  • Traditionally organized by serogroups of capsular polysaccharide
    • A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically

Epidemiology

  • Six serogroups cause essentially all disease: A, B, C, W, X, and Y
  • In Canada, serogroups B, C, W-135 and Y are the most common causes, with B being the most commonly reported
    • Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks

References

  1. ^  Charles Feldman, Ronald Anderson. Meningococcal pneumonia: a review. Pneumonia. 2019;11(1). doi:10.1186/s41479-019-0062-0.