Neisseria meningitidis: Difference between revisions

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Neisseria meningitidis
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[[Category:Infectious diseases]]
[[Category:Infectious diseases]]


== Background ==
==Background==


=== Microbiology ===
===Microbiology===


* [[Gram stain::Gram-negative]] [[Cell shape::coccus|diplococcus]]
*[[Gram stain::Gram-negative]] [[Cell shape::coccus|diplococcus]]
* Traditionally organized by serotyping of capsular polysaccharide
*Traditionally organized by serogroups of capsular polysaccharide
** A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically
**A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically


=== Epidemiology ===
===Epidemiology===


* Six serogroups cause essentially all disease: A, B, C, W, X, and Y
*Six serogroups cause essentially all disease: A, B, C, W, X, and Y
* In Canada, B, C, W-135 and Y are the most common causes, with B being the most commonly reported
*In Canada, serogroups B, C, W-135 and Y are the most common causes, with B being the most commonly reported
** Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks
**Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks

Revision as of 16:40, 31 July 2020


Background

Microbiology

  • Gram-negative diplococcus
  • Traditionally organized by serogroups of capsular polysaccharide
    • A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically

Epidemiology

  • Six serogroups cause essentially all disease: A, B, C, W, X, and Y
  • In Canada, serogroups B, C, W-135 and Y are the most common causes, with B being the most commonly reported
    • Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks

References

  1. ^  Charles Feldman, Ronald Anderson. Meningococcal pneumonia: a review. Pneumonia. 2019;11(1). doi:10.1186/s41479-019-0062-0.