Oseltamivir: Difference between revisions

Revision as of 14:46, 31 July 2020

Indication	CrCl >60	CrCl >30 to 60 mL/min	CrCl >10 to 30 mL/min	IHD
Influenza (treatment)	Usual dose	30 mg PO bid	30 mg PO daily	30 (low-flux) to 75 (high-flux) mg PO after dialysis
Influenza (prophylaxis)	Usual dose	30 mg PO daily	30 mg PO every other day	30 mg PO after every other dialysis

@@ Line 1: / Line 1: @@
-== Background ==
+==Background==
-=== Mechanism of Action ===
+===Mechanism of Action===
-* Inhibits viral neuraminidase
+*Inhibits viral neuraminidase
-== Dose ==
-=== Adults ===
-* Influenza (treatment): 75 mg PO bid
-* Influenza (prophylaxis): 75 mg PO daily
+==Dose==
-==== Renal Dosing ====
+===Adults===
-{| style="wikitable"
-! Indication
+*Influenza (treatment): 75 mg PO bid
-! CrCl >60
+*Influenza (prophylaxis): 75 mg PO daily
-! CrCl >30 to 60 mL/min
-! CrCl >10 to 30 mL/min
+====Renal Dosing====
-! IHD
+{| class="wikitable" style="wikitable"
+!Indication
+!CrCl >60
+!CrCl >30 to 60 mL/min
+!CrCl >10 to 30 mL/min
+!IHD
 |-
-| Influenza (treatment)
+|Influenza (treatment)
-| Usual dose
+|Usual dose
-| 30 mg PO bid
+|30 mg PO bid
-| 30 mg PO daily
+|30 mg PO daily
-| 30 (low-flux) to 75 (high-flux) mg PO after dialysis
+|30 (low-flux) to 75 (high-flux) mg PO after dialysis
 |-
-| Influenza (prophylaxis)
+|Influenza (prophylaxis)
-| Usual dose
+|Usual dose
-| 30 mg PO daily
+|30 mg PO daily
-| 30 mg PO every other day
+|30 mg PO every other day
-| 30 mg PO after every other dialysis
+|30 mg PO after every other dialysis
 |}