Immune reconstitution inflammatory syndrome: Difference between revisions
From IDWiki
(Created page with "== Background == * Two main forms: ** '''Unmasking''': an underlying, previously undiagnosed infection becomes clinically apparent following immune reconstitution ** '''Parad...") |
No edit summary |
||
| Line 1: | Line 1: | ||
== |
==Background== |
||
* |
*Two main forms: |
||
** |
**'''Unmasking''': an underlying, previously undiagnosed infection becomes clinically apparent following immune reconstitution |
||
** |
**'''Paradoxical''': a diagnosed and treated infection worsens following immune reconstitution |
||
=== |
=== Microbiology === |
||
* Mycobacteria |
|||
| ⚫ | |||
** [[Mycobacterium tuberculosis]] |
|||
| ⚫ | |||
** [[Mycobacterium avium complex]] |
|||
* Fungi |
|||
** [[Cryptococcus neoformans]] |
|||
* Viruses |
|||
** [[Cytomegalovirus]] |
|||
** [[Kaposi sarcoma-associated herpesvirus]] |
|||
===Risk Factors=== |
|||
| ⚫ | |||
| ⚫ | |||
== Clinical Manifestations == |
|||
* Varies by underlying infection |
|||
* Onset usually a month following starting antiretrovirals, but can be up to a year |
|||
[[Category:HIV]] |
[[Category:HIV]] |
||
Revision as of 01:54, 24 July 2020
Background
- Two main forms:
- Unmasking: an underlying, previously undiagnosed infection becomes clinically apparent following immune reconstitution
- Paradoxical: a diagnosed and treated infection worsens following immune reconstitution
Microbiology
- Mycobacteria
- Fungi
- Viruses
Risk Factors
- High viral load
- Low CD4 count
Clinical Manifestations
- Varies by underlying infection
- Onset usually a month following starting antiretrovirals, but can be up to a year
