Nutritionally variant streptococci: Difference between revisions

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* [[Subacute bacterial endocarditis]] is the most well-known disease association
* [[Subacute bacterial endocarditis]] is the most well-known disease association


== Management ==

* Susceptibilities shown below are from one small study[[CiteRef::kanamoto2018an]]

{| class="wikitable"
!Antibiotic
![[Abiotrophia defectiva]]
![[Granulicatella adiacens]]
![[Granulicatella elegans]]
|-
|Penicillin
|57%
|82%
|100%
|-
|Ampicillin
|86%
|100%
|100%
|-
|Piperacillin
|0%
|53%
|100%
|-
|Cefazolin
|29%
|88%
|100%
|-
|Ceftriaxone
|100%
|76%
|100%
|-
|Ceftazidime
|0%
|0%
|50%
|-
|Imipenem
|100%
|100%
|100%
|-
|Gentamicin
|0%
|0%
|0%
|-
|Ciprofloxacin
|100%
|18%
|17%
|-
|Minocycline
|57%
|94%
|100%
|-
|Vancomycin
|100%
|100%
|83%
|-
|TMP-SMX
|14%
|0%
|17%
|}
[[Category:Gram-positive cocci]]
[[Category:Gram-positive cocci]]

Revision as of 19:17, 11 March 2022

Background

  • Require pyridoxine (vitamin B6) supplementation to group
  • Also called pyridoxal-dependent or stalliting streptococci

Organisms

Clinical Manifestations

Management

  • Susceptibilities shown below are from one small study1
Antibiotic Abiotrophia defectiva Granulicatella adiacens Granulicatella elegans
Penicillin 57% 82% 100%
Ampicillin 86% 100% 100%
Piperacillin 0% 53% 100%
Cefazolin 29% 88% 100%
Ceftriaxone 100% 76% 100%
Ceftazidime 0% 0% 50%
Imipenem 100% 100% 100%
Gentamicin 0% 0% 0%
Ciprofloxacin 100% 18% 17%
Minocycline 57% 94% 100%
Vancomycin 100% 100% 83%
TMP-SMX 14% 0% 17%

References

  1. ^  Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima. Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria. Medicines. 2018;5(4):129. doi:10.3390/medicines5040129.