Nutritionally variant streptococci: Difference between revisions

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* [[Subacute bacterial endocarditis]] is the most well-known disease association
 
* [[Subacute bacterial endocarditis]] is the most well-known disease association
   
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== Management ==
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  +
* Susceptibilities shown below are from one small study[[CiteRef::kanamoto2018an]]
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{| class="wikitable"
  +
!Antibiotic
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![[Abiotrophia defectiva]]
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![[Granulicatella adiacens]]
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![[Granulicatella elegans]]
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|-
  +
|Penicillin
  +
|57%
  +
|82%
  +
|100%
  +
|-
  +
|Ampicillin
  +
|86%
  +
|100%
  +
|100%
  +
|-
  +
|Piperacillin
  +
|0%
  +
|53%
  +
|100%
  +
|-
  +
|Cefazolin
  +
|29%
  +
|88%
  +
|100%
  +
|-
  +
|Ceftriaxone
  +
|100%
  +
|76%
  +
|100%
  +
|-
  +
|Ceftazidime
  +
|0%
  +
|0%
  +
|50%
  +
|-
  +
|Imipenem
  +
|100%
  +
|100%
  +
|100%
  +
|-
  +
|Gentamicin
  +
|0%
  +
|0%
  +
|0%
  +
|-
  +
|Ciprofloxacin
  +
|100%
  +
|18%
  +
|17%
  +
|-
  +
|Minocycline
  +
|57%
  +
|94%
  +
|100%
  +
|-
  +
|Vancomycin
  +
|100%
  +
|100%
  +
|83%
  +
|-
  +
|TMP-SMX
  +
|14%
  +
|0%
  +
|17%
  +
|}
 
[[Category:Gram-positive cocci]]
 
[[Category:Gram-positive cocci]]

Revision as of 15:17, 11 March 2022

Background

  • Require pyridoxine (vitamin B6) supplementation to group
  • Also called pyridoxal-dependent or stalliting streptococci

Organisms

Clinical Manifestations

Management

  • Susceptibilities shown below are from one small study1
Antibiotic Abiotrophia defectiva Granulicatella adiacens Granulicatella elegans
Penicillin 57% 82% 100%
Ampicillin 86% 100% 100%
Piperacillin 0% 53% 100%
Cefazolin 29% 88% 100%
Ceftriaxone 100% 76% 100%
Ceftazidime 0% 0% 50%
Imipenem 100% 100% 100%
Gentamicin 0% 0% 0%
Ciprofloxacin 100% 18% 17%
Minocycline 57% 94% 100%
Vancomycin 100% 100% 83%
TMP-SMX 14% 0% 17%

References

  1. ^  Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima. Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria. Medicines. 2018;5(4):129. doi:10.3390/medicines5040129.