Lead toxicity: Difference between revisions

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== Risk Factors ==
== Background ==


=== Pathophysiology ===
* Occupational exposure to lead
** Battery manufacturing
** Plumbing
** Mining
** Painting
** Paper hanging
** Auto repair


* Lead has multisystem effects, and is a powerful neurotoxin
== Clinical Manifestations ==


===Risk Factors===
* Acute exposure

** Abdominal pain and constipation
*Occupational exposure to lead:
** Headache, cognitive deficits, and peripheral neuropathy
**Battery manufacturing
** Myalgias and arthralgias
**Plumbing
** Anemia
**Mining
** Anorexia
**Painting
* Chronic exposure
**Paper hanging
** Fatigue and insomnia
**Auto repair
** Hypertension

** Neuropsychiatric symptoms
==Clinical Manifestations==
** Nephropathy

** Miscarriages and stillbirths Investigations
*Acute exposure
* Labs:
**[[Abdominal pain]] and [[constipation]]
** CBC showing microcytic anemia
**[[Headache]], cognitive deficits, and [[peripheral neuropathy]]
** Peripheral blood film showing basophilic stippling
**Myalgias and arthralgias
**[[Anemia]]
**Anorexia
*Chronic exposure
**Fatigue and [[insomnia]]
**[[Hypertension]]
**Neuropsychiatric symptoms
**[[Nephropathy]]
**[[Miscarriage]] and [[stillbirth]]

== Investigations ==

*Labs:
**CBC showing [[microcytic anemia]]
**Peripheral blood film showing basophilic stippling


[[Category:Toxicology]]
[[Category:Toxicology]]

Revision as of 13:44, 23 October 2020

Background

Pathophysiology

  • Lead has multisystem effects, and is a powerful neurotoxin

Risk Factors

  • Occupational exposure to lead:
    • Battery manufacturing
    • Plumbing
    • Mining
    • Painting
    • Paper hanging
    • Auto repair

Clinical Manifestations

Investigations

  • Labs: