Syphilis in pregnancy: Difference between revisions

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== Background ==

* Risk of transmission to fetus
** Primary and secondary syphilis: 70 to 100%
** Early latent syphilis: 40%
** Late latent syphilis: 10%

==Management==
==Management==

* For primary, secondary, or early latent syphilis: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 1-2 doses
* For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 3 doses
*For primary, secondary, or early latent syphilis: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 1-2 doses
*For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 3 doses
* For tertiary neurosyphilis, treat as usual
*For tertiary neurosyphilis, treat as usual
* Postpartum, follow guidelines for [[congenital syphilis]] to decide whether and how to treat the neonate
*Postpartum, follow guidelines for [[congenital syphilis]] to decide whether and how to treat the neonate


[[Category:Infectious diseases]]
[[Category:Infectious diseases]]

Revision as of 18:31, 15 August 2020

Background

  • Risk of transmission to fetus
    • Primary and secondary syphilis: 70 to 100%
    • Early latent syphilis: 40%
    • Late latent syphilis: 10%

Management

  • For primary, secondary, or early latent syphilis: benzathine penicillin G 2.4 million units IM weekly for 1-2 doses
  • For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: benzathine penicillin G 2.4 million units IM weekly for 3 doses
  • For tertiary neurosyphilis, treat as usual
  • Postpartum, follow guidelines for congenital syphilis to decide whether and how to treat the neonate