Infections after hematopoietic stem cell transplantation: Difference between revisions
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| '''Late post-engraftment'''<br/>after 1 year |
| '''Late post-engraftment'''<br/>after 1 year |
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| Immunosuppresing meds, chronic GVHD |
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| [[Encapsulated bacteria]], [[Listeria]], [[Salmonella]], [[Nocardia]] |
| [[Encapsulated bacteria]], [[Listeria]], [[Salmonella]], [[Nocardia]] |
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| [[VZV]], [[CMV]], respiratory/enteric viruses |
| [[VZV]], [[CMV]], respiratory/enteric viruses |
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Revision as of 18:50, 17 May 2020
Timeline of Infections
| Time | Risk factors | Bacteria | Viruses | Fungi | Parasites |
|---|---|---|---|---|---|
| Pre-engraftment day 0 to 30 |
Neutropenia, mucositis, and central lines | GPCs and GNBs | BK virus, HSV, and resp/enteric viruses | Candida and Aspergillus | Strongyloides |
| Early post-engraftment to day 100 |
Immunosuppressing meds, acute GVHD, central lines | GPCs, encapsulated bacteria, Listeria, Salmonella, Nocardia | HSV, CMV, HHV-6, adenovirus, resp/enteric viruses | Aspergillus, other molds, PJP | Strongyloides, Toxoplasma |
| Mid post-engraftment to 1 year |
Immunosuppressing meds, chronic GVHD | Encapsulated bacteria, Listeria, Salmonella, Nocardia | VZV, EBV (and PTLD), CMV, respiratory/enteric viruses | Aspergillus, other molds, PJP | |
| Late post-engraftment after 1 year |
Immunosuppresing meds, chronic GVHD | Encapsulated bacteria, Listeria, Salmonella, Nocardia | VZV, CMV, respiratory/enteric viruses |
Further Reading
- Life-threatening Infection in Transplant Recipients. Crit Care Clin. 2013 Oct;29(4):953-73. doi: 10.1016/j.ccc.2013.06.012
