Antifungal spectrum of activity: Difference between revisions

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Revision as of 16:19, 9 September 2019

Organism AmB Fluc Itra Vori Posa Anidula Caspo Mica Flucyt
Aspergillus spp. + + + + + + +
A. flavus ± + + + + + +
A. fumigatus + + + + + + +
A. terreus + + + + + +
A. niger + ± + + + + +
Candida spp. + + + + + + + + +
C. albicans + + + + + + + + +
C. glabrata + ± ± + + + + + +
C. krusei + ± + + + + + ±
C. lusitaniae + + + + + + + +
C. parapsilosis + + + + + ± ± ± +
C. tropicalis + + + + + + + + +
Cryptococcus neoformans + + + + + +
Coccidioides spp. + + + + + ± ± ±
Blastomyces + + + + + ± ± ±
Histoplasma spp. + + + + + ± ± ±
Fusarium spp. ± + +
Scedosporium apiospermum ± ± + +
Scedosporium prolificans ± ±
Zygomycetes ± +

Aspergillus ustus is resistant to azoles and echinocandins, and variable resistance to amphotericin (though still susceptible to terbinafine)

Source: Elizabeth S. Dodds Ashley, Russell Lewis, James S. Lewis, Craig Martin, David Andes, Pharmacology of Systemic Antifungal Agents, Clinical Infectious Diseases, Volume 43, Issue Supplement_1, 1 August 2006, Pages S28–S39, https://doi.org/10.1086/504492