Rifampin: Difference between revisions

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* Inhibits bacterial DNA-dependent RNA polymerase
* Never given alone due to rapid resistance
* Never given alone due to rapid resistance
* Adverse effects include drug-drug interactions, rash, hepatitis, influenza-like illness, neutropenia, and thrombocytopenia
* Beware drug interactions
* Avoid in liver failure
* Avoid in liver failure



Revision as of 03:08, 14 November 2019

  • Inhibits bacterial DNA-dependent RNA polymerase
  • Never given alone due to rapid resistance
  • Adverse effects include drug-drug interactions, rash, hepatitis, influenza-like illness, neutropenia, and thrombocytopenia
  • Avoid in liver failure

References

  1. ^  Gousia Dhhar, Jeanine McColl, Ian Kitai, Deborah M. Levy, Ruud H.J. Verstegen. Rifampin-induced flu-like syndrome with shock in a patient with tuberculosis infection. Canadian Medical Association Journal. 2023;195(34):E1151-E1153. doi:10.1503/cmaj.230317.